Potential Benefits
- Supports healthy methylation & homocysteine levels
- Powerful heart health support
- Supports healthy cognition & brain function
Key ingredients and features
- Folate (L-methylfolate or 5-MTHF): Folic acid, regardless of its form—whether L-methylfolate or 5-methyltetrahydrofolate—can easily be converted into a 5-carbon unit used to reduce or eliminate homocysteine through the methionine biochemical pathway, thus facilitating all methylation. 5-Methyltetrahydrofolate is the predominant form of folate in the body and is superior to classical folic acid.
- Vitamin B12 comes in two forms: Methylcobalamin and Adenosylcobalamin. These vitamin B12 isoforms act as linkers involved in homocysteine metabolism. This is how vitamin B12 manages to accept a methyl group from 5-methylfolate and helps convert homocysteine back to methionine, which is a useful amino acid.
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R-5-P (riboflavin 5’-phosphate):
is the biologically active form of vitamin B2. It acts as a coenzyme for two enzymes, MTRR and MTHFR, contributing to methionine formation and the elimination of homocysteine. Pyridoxine is also needed for energy from glucose metabolism.
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P-5-P (pyridoxal 5’-phosphate):
is the active form of vitamin B6 that is directly recyclable and is required by more than 140 enzyme reactions in the human body. P-5-P is also helpful for the conversion, through CBS and CTH enzymes, of homocysteine to cysteine, which is a component of glutathione and taurine—substances involved in detoxification.
- Betaine (TMG): is a potent methyl supplier. This nutrient is extremely useful for those suffering from the MTHFR mutation. It acts as a coenzyme for the BHMT enzyme, which converts homocysteine to methionine, particularly in liver cells
Who is Homocysteine Nutrients intended for?
Homocysteine Nutrients is intended for those seeking support for homocysteine metabolism, methylation, blood flow, cardiovascular health, and brain health in an easy, single capsule serving.